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In a 2016 study published in Scientifica (Cairo), Egyptian researchers examined the effects of titanium dioxide nanoparticles on the organs of mice by orally administering the food additive daily, for five days. The results showed that the exposure produced “mild to moderate changes in the cytoarchitecture of brain tissue in a time dependent manner.” Furthermore, “Comet assay revealed the apoptotic DNA fragmentation, while PCR-SSCP pattern and direct sequencing showed point mutation of Presenilin 1 gene at exon 5, gene linked to inherited forms of Alzheimer’s disease.” The researchers wrote: “From these findings, “the present study concluded that TiO2NPs is genotoxic and mutagenic to brain tissue which in turn might lead to Alzheimer’s disease incidence.”

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Modern lithopone factories are at the forefront of this revolution. They employ cutting-edge technology to reduce energy consumption and optimize production processes. Advanced filtration systems ensure that the end product is free from impurities, while closed-loop systems recycle water and other byproducts, significantly reducing the environmental footprint. Moreover, these facilities are increasingly powered by renewable energy sources, aligning manufacturing practices with sustainability goals.

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The titanium dioxide industry is a crucial sector in the global chemical market, with a wide range of applications in various industries such as paints, plastics, paper, and textiles. Titanium dioxide, also known as TiO2, is a white pigment that is widely used for its high refractive index and excellent stability. The demand for titanium dioxide has been steadily increasing over the years, driven by the growing construction and automotive industries.

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